| Type | Date | Time | Venue | Away | Home | Score |
|---|---|---|---|---|---|---|
| Fri Feb 28 | 2:00 pm | Concordia University | Boston College | Concordia | 16 - 13 | |
| Fri Feb 28 | 5:00 pm | University of Missouri | Ole Miss | Missouri | 4 - 11 | |
| Fri Feb 28 | 6:00 pm | UC Santa Barbara | USC | UC Santa Barbara | 14 - 7 | |
| Fri Feb 28 | 6:00 pm | Arizona State University - West Campus | Georgia Tech | Arizona State | 15 - 6 | |
| Fri Feb 28 | 7:00 pm | University of Missouri | Minnesota | Indiana | 11 - 4 | |
| Fri Feb 28 | 7:00 pm | Cook Pavillion | Kansas | Nebraska | 22 - 6 | |
| Fri Feb 28 | 7:00 pm | Pensacola Catholic HS | Western Michigan | Texas Christian | 11 - 13 | |
| Fri Feb 28 | 7:00 pm | Allison North Stadium | Dayton | Missouri State | 13 - 7 | |
| Fri Feb 28 | 7:00 pm | Tennessee-Sutherland Fields | Virginia Tech | Tennessee | 15 - 5 | |
| Fri Feb 28 | 7:30 pm | Rancho Bernardo HS | Texas | San Diego State | 7 - 8 | |
| Fri Feb 28 | 7:30 pm | UCLA | Georgia | UCLA | 9 - 6 | |
| Fri Feb 28 | 7:30 pm | Utah State University | Wyoming | Utah State | 13 - 14 | |
| Fri Feb 28 | 9:00 pm | Liberty Men's Lacrosse Field | George Washington | Liberty | 2 - 18 |
Legend
- Divisional Game
- Out
- Playoff Game
- Scrimmage
- Tournament Game
- Active
- Cancelled Game
- Forfeit
- Live
- No Contest
- Postponed
- Rescheduled Game